Our Pipeline

HE staining score: Reflects the overall situation of tissue repair, inflammatory response, and structural integrity. Redder color indicates better granulation tissue formation.

Masson staining (collagen deposition) results show significantly reduced collagen precipitation, indicating that the drug acts during skin repair with less fibrosis and less scar formation.

F4/80+CD206+ double-positive cell proportion results suggest: M2 macrophages have repair effects in the late stage of immune response. The drug significantly promotes M2 polarization, indicating that the drug's action on the mouse immune environment may tend toward repair and anti-inflammatory effects.

F4/80+CD45+ double-positive cell proportion results suggest: M1 macrophages may be related to inflammatory response or immune activity. The drug shows a trend of inhibiting M1 polarization.

Flow cytometry results show that the drug can significantly enhance macrophage M2 polarization and inhibit M1 polarization.

Immunofluorescence results show that the drug can significantly enhance macrophage M2 polarization and inhibit M1 polarization.

Western blot results show significant inhibition of macrophage NF-κB, PI3K/AKT, and NLRP3 inflammasome pathway signaling expression.